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Psilocybin, a naturally occurring substance found in magic mushrooms or master mushrooms, is a chemical compound that has strong psychoactive effects. Some research has shown that taking psilocybin in some people with obsessive-compulsive disorder (OCD) can significantly improve its signs and symptoms. These studies have shown that psilocybin, as a psychoactive substance, can help control OCD symptoms and in some cases can even reduce repetitive and compulsive behaviors. However, before using psilocybin or any other substance, be sure to check with your doctor to make sure it is the right and safe way to treat your OCD.

OCD (obsessive-compulsive disorder) is a mental disorder that is associated with irrational repetition of thoughts and worries (obsessions) and performing repetitive and compulsive actions (compulsions). This disorder can affect people's daily life and severely reduce the quality of life. Research has shown that psilocybin, a chemical compound found in chanterelle mushrooms, may be effective in improving OCD symptoms.

Psilocybin is a complex compound that, upon entering the brain, causes strong psychoactive effects with rapid action. This compound in the brain quickly goes to the precursor of serotonin (5-HT2A) and by interacting with it, it creates changes in different neural networks.

Research conducted on the effects of psilocybin and ocd shows that this compound can be effective as a psychoactive agent in improving the signs and symptoms of OCD. One study of people with OCD found that taking a single session of psilocybin under the supervision of a doctor may lead to significant improvement in OCD symptoms. Other research has also shown that psilocybin can affect brain function and alter abnormal activity patterns in neural networks associated with OCD.

Among the effects of psilocybin in improving OCD symptoms are:

1. Reducing the intensity of obsessions and compulsions: taking psilocybin may reduce the intensity and recurrence of obsessions and compulsions.

2. Increase mental flexibility: Psilocybin can help people to effectively disengage from their obsessive thoughts and encourage the mind to be more flexible in the face of these thoughts.

3. Experience more reality: with the effect of psilocybin, people may have deeper experiences of reality that can cause a change in attitude to ephedra. In addition to the positive effects, it should be noted that the use of psilocybin may also be accompanied by side effects such as anxiety, exacerbation of obsessions. , mood changes and unpleasant experiences such as hallucinations or false experiences.

Also, psilocybin consumption should be done under the supervision and guidance of professionals and in a safe and controlled environment. This compound is not legal in many countries and its use without legal authorization may cause legal problems.

Therefore, before using psilocybin or any other substance to treat OCD, be sure to consult your doctor and it is better to consider other treatment strategies such as psychotherapy or medications prescribed by the doctor. Also, things like your medical history, medications, and your physical and mental condition should also be taken into consideration in making a decision.

A recent study by Israeli scientists found that the mushroom extract may demonstrate superior effectiveness compared to chemically synthesized psilocybin, especially in stimulating neuroplasticity and promoting the development of new connections between nerve cells - a very important property. This breakthrough opens up potential applications for treating depression, PTSD and schizophrenia. The study results were published in the journal Molecular Psychiatry.

In work led by researchers Dr. Tsuri Lifshitz and psychiatrist Prof. Bernard Lehrer from Hadassah Hebrew University Medical Center, with the participation of graduate student Orrom Shahar and Dr. Alexander Botvinnik, the scientists found that a mushroom extract containing psilocybin may have more potent and long-lasting effects on synaptic plasticity in the brain. compared to chemically synthesized psilocybin.

Millions of people around the world suffer from mental disorders, and many patients remain refractory to existing pharmaceutical treatments. Alarming statistics show that 40% of people suffering from depression find no relief from currently available medications, a similar trend among people with OCD.

Moreover, with approximately 0.5% of the population suffering from schizophrenia, there is an urgent need for innovative solutions tailored to those who do not benefit from existing medications.

Preliminary study results shed light on the discrepancy in effectiveness between psilocybin-containing mushroom extract and chemically synthesized psilocybin. Notably, the extract increased levels of synaptic proteins associated with neuroplasticity in key brain regions including the frontal cortex, hippocampus, amygdala, and striatum.

Metabolomic analysis also revealed notable differences between the mushroom extract containing psilocybin and ocd chemically synthesized psilocybin. The extract demonstrated a distinct metabolic profile related to oxidative stress and energy production pathways.

These findings open up new possibilities for the therapeutic use of natural psychedelic compounds, offering hope to those who have found little relief in traditional psychiatric treatments. As demand for innovative solutions continues to grow, psychedelic drug research represents a critical avenue for the development of novel and personalized medicines.

Additionally, Western medicine has historically favored the isolation of active compounds rather than the use of extracts, primarily to achieve better control over doغير مجاز مي باشدes and the onset of known effects during treatment. The challenge with extracts has been that in the past it has not been possible to consistently produce an accurate product with a consistent composition. In contrast, ancient medical practices, especially those that attributed therapeutic benefits to psychedelic medicine, included the use of extracts or whole foods, such as consuming the entire mushroom.

The main problem with natural extracts is achieving a stable composition, especially in plants, but mushrooms are unique in this regard. The composition of fungi is influenced by their growth environment, including factors such as substrate composition, CO2/O2 ratio, light exposure, temperature and microbiological environment. Despite these factors, controlled cultivation makes it possible to “tame” the mushrooms and obtain a reproducible extract.